Tetteh played professional club football in Ghana for Great Mao Mao, Golden Pods, Hearts of Oak, Zebi; in Nigeria for ACB, Julius Berger, Bendel United and Iwuanyanwu; and in Bangladesh.
Tetteh began his coaching career in 1995 with Kotobabi Powerlines, before joining Liberty Professionals a year later. Tetteh became Assistant Manager of the Ghana under-17 team in 2001 - taking full control a year later - before moving to the Ghana under-23 team in 2003. He later became an Assistant to the full national team.
He was appointed caretaker manager of the Ghanaian national team in June 2008, a position he held until August 2008.Tetteh was appointed manager of the Rwandan national side in February 2010, leaving his dual position as manager of the Ghana under-20 national team and Ghanaian club side Liberty Professionals. Tetteh guided the Ghana under-20 team to the 2009 FIFA U-20 World Cup, becoming the first African team to win the competition.
As a consequence, Tetteh was nominated for the CAF Coach of the Year Award. He was also honored by veteran coach Cecil Jones Attuquayefio, who 'knighted' Tetteh.
Silas Tetteh had his first stint with the junior side in 1999 playing the role of an assistant coach to Cecil Jones Attuquayefio at the FIFA U-17 World Cup in New Zealand where Ghana picked up bronze.
In 2002, Silas Tetteh took charge of the Black Starlets team but Ghana failed to qualify for the African Junior Championship.